Ferry firm SeaFrance is to shed 127 jobs in Dover after it was liquidated by a French court and told to cease activity.
The Tribunal de Commerce decided SeaFrance's future after a bailout by the French government was ruled illegal by the European Commission.
The court also said an offer by a cooperative of employees was not acceptable.
Hundreds of jobs in France are also expected to be lost.
Three ferries were operated by SeaFrance on the Dover to Calais route. The service was suspended in November.
Conservative MP for Dover and Deal Charlie Elphicke said: "It is a real concern for the... people in Dover who have worked for SeaFrance and also their families.
"This is a difficult day and I think the heart of the whole community goes out to them.